Dy passenger trains crashed about 76km south of Cairo on Sunday, causing at least four victims and injuring 88 others.
The Ministry of Health of Egypt has announced the event.
The state railway authority said that a train traveling from Giza to Fayoum ran into another who traveled from Cairo to Aswan, taking several cars off track.
President Abdel Fattah al-Sisi ordered a quick investigation and said anyone found negligent should be held responsible, according to a separate statement.
Emergency teams were cleaning up ruins to restore services on the Cairo-Egypium Line, the railway authority said, without providing any indication of how long this would last.